BIO-DL was established in 2013, located in Songjiang District, Shanghai, China, with an office area of more than 3,000 square meters; it is a comprehensive company integrating R&D, production and trade, and has a worldwide sales network and service centers. BIO-DL is dedicated to offering high quality technology products and services, as well as creating pleasant experiences for the users. BIO-DL has passed CE certification, ISO9001 quality management system certification and ISO13485 medical device quality management system certification. In addition, we have 2 software copyrights and 7 utility model patents.
Product Introduction of Thermal Cycler Gene Amplification Instrument for Laboratory
The gene amplification instrument adopts customized American original semiconductor refrigeration chips, with a maximum temperature change rate of the module greater than 4.5 ℃/S and more than 1 million cycles. Advanced thermoelectric refrigeration technology and PID temperature control technology have taken the overall performance to a new height: high temperature control accuracy, fast temperature rise and fall rate, uniform module temperature, and low-noise operation. Equipped with a 30 ℃ grace gradient function, it can be used to optimize experimental conditions and meet demanding experimental requirements; 10.1-inch color touch screen, industrial grade operating system, can easily achieve 7 * 24-hour continuous error free operation; Multiple file storage methods: machine memory and USB external storage; Carry experimental data with you, file storage is no longer restricted; Optional IoT module enables easy remote operation and instrument after-sales service management.
Characteristic of Thermal Cycler Gene Amplification Instrument for Laboratory
1. Accurate temperature control
High temperature accuracy: It can accurately control the temperature of the reaction system near the set value, and the temperature accuracy in the working area can reach ≤± 0.1 ℃, ensuring that the PCR reaction is carried out under appropriate temperature conditions and reducing the impact of temperature deviation on the amplification results.
Good temperature uniformity: Ensure minimal temperature differences between reaction holes or at different positions inside the reaction tube, with a temperature uniformity of ≤± 0.2 ℃ in the working area, allowing each reaction system to obtain consistent amplification conditions and improving the repeatability and reliability of the experiment.
Rapid temperature rise and fall: equipped with efficient heating and cooling systems, the heating/cooling speed can reach 4.5 ℃/S, which can complete the conversion of different temperature stages such as high-temperature denaturation, low-temperature annealing, and temperature appropriate extension in a short time, shortening the entire PCR reaction time.
2. Efficient amplification
Rapid completion of reaction: With its fast thermal cycling ability and precise temperature control, gene amplification can be completed in a shorter time, greatly improving experimental efficiency compared to traditional gene amplification methods. For example, some rapid PCR machines can complete amplification reactions in about 1 hour.
3. Reliable results
Strong specificity: By designing specific primers, target gene fragments can be amplified specifically, reducing the generation of non-specific amplification products, making experimental results more accurate and reliable, and helping to accurately detect and analyze specific gene sequences.
High sensitivity: It can detect extremely low levels of target genes, even if the initial DNA or RNA content in the sample is very small, it can be amplified exponentially to a detectable level, with a minimum resolution of 1 copy, which can meet the detection needs of trace samples.
Good repeatability: High precision temperature control, stable thermal cycling system, and strict experimental condition control enable the gene amplification instrument to obtain consistent amplification results in multiple experiments or between different laboratories. The experimental repeatability CV is ≤ 2.1%, providing a reliable basis for subsequent data analysis and comparison.
4. Easy to operate
User friendly interface: Equipped with a simple and intuitive operating interface, usually with a display screen and operation buttons, it is convenient for users to set parameters, edit programs, monitor experiments, and other operations. Some instruments also have interfaces in multiple languages such as Chinese, reducing the difficulty of operation. Even first-time users can quickly get started.
Convenient data processing: Some gene amplifiers come with built-in data processing and analysis software, which can monitor and record the amplification reaction process in real time, automatically calculate and analyze amplification results, and store, print or export data for users to conduct subsequent data analysis and report writing.
5. Good compatibility
Diverse sample types: It can be applied to various types of samples, such as blood, tissue, body fluids, bacterial strains, cells, gene banks, etc. Whether it is clinical samples, scientific research samples, or environmental samples, it can be used as a template for gene amplification to meet the needs of different fields and experiments.
Strong universality of reagents: It can be compatible with various PCR kits at home and abroad, as well as different brands and types of reagents. Users can choose suitable reagents according to their experimental needs and costs, which improves the applicability of the instrument.
Application of Thermal Cycler Gene Amplification Instrument for Laboratory
1. Medical field
Disease diagnosis: It can detect the nucleic acid sequence of pathogens, such as AIDS virus, hepatitis B virus, tuberculosis, etc., to achieve early diagnosis of diseases and efficacy evaluation. It can also detect genetic variations related to genetic diseases such as thalassemia and hemophilia, providing a basis for the diagnosis of genetic diseases. It can also detect tumor markers and tumor genes, such as carcinoembryonic antigen, P53 gene, etc., to assist in early screening, monitoring, and treatment efficacy evaluation of tumors.
Organ transplantation and transfusion typing: Through genotyping technology, human leukocyte antigen (HLA) genotyping, blood type genotyping, etc. are performed to provide accurate basis for organ transplantation typing and transfusion typing, improving the success rate of transplantation and transfusion safety.
Personalized medicine: Analyze the genetic characteristics of patients, predict their response and tolerance to specific drugs, help doctors develop personalized treatment plans, improve drug efficacy, and reduce adverse reactions.
2. Field of biological research
Gene cloning and expression analysis: Quickly obtaining a large number of specific DNA fragments, providing materials for gene function research, genetic engineering, etc. It can also be used to analyze the changes in gene expression levels in different tissues, developmental stages, or environmental conditions, revealing the expression regulation mechanism of genes.
Genetic mutation and polymorphism detection: Detecting genetic variations in an individual's genome, such as single nucleotide polymorphisms (SNPs), insertion/deletion mutations, etc., to provide data support for genetic research and evolutionary biology research.
Research on species evolution and phylogenetic relationships: amplifying and analyzing gene sequences of different species or different populations of the same species, comparing gene differences and similarities, and inferring the evolutionary history and phylogenetic relationships of species.
Packaging & shipping of Thermal Cycler Gene Amplification Instrument for Laboratory
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FAQ
Q: How about quality of the goods?
A: All the running products comply with CE standards.
Independent quality inspection team, conducting multiple inspections and random inspections from parts supply to product dispatch.
Q: Is OEM service available.
A: All of the running products are available for OEM customization, including logo and package.
